Big Muddy Creek Bridge (Clay County, Illinois)
Built 1923
Through truss bridge over Big Muddy Creek on Fr-2114 (Old US 50)
Closed to all traffic

Branch Friends Creek US 50 Bridge (Martin County, Indiana)
Built ca. 1930; rehabilitated 1997
Concrete arch bridge over Branch Friends Creek on US 50 in Loogootee
Open to traffic

Branch Hogan Creek Old US 50 Bridge (Dearborn County, Indiana)
Built ca. 1930
Concrete arch bridge over a branch of Hogan Creek on Old US 50 in Aurora
Open to traffic

Cacapon River Bridge (Hampshire County, West Virginia)
Built 1933
Through truss bridge over Cacapon River on US 50 T in Capon Bridge
Open to traffic

Cheat River Bridge (Preston County, West Virginia)
Built 1932
Truss bridge over Cheat River on US 50
Open to traffic

Chesapeake Bay Bridge (Anne Arundel County, Maryland)
Built 1951; rehabilitated 1988
Suspension bridge over Chesapeake Bay on US 50
Open to traffic

Clear Spring Creek Old US 50 Bridge (Jackson County, Indiana)
Built 1987
Concrete arch bridge over Clear Spring Creek on Old US 50
Open to traffic

Cleves Bridge (Hamilton County, Ohio)
Built 1959-60
Four-span through truss bridge over the Great Miami River on westbound US 50 at Cleves
Open to two lanes of westbound traffic

Davisson Run Bridge (Harrison County, West Virginia)
Built 1918
Concrete arch bridge over Davisson Run on US 50 in Bridgeport
Open to traffic

Dawson Creek US 50 Bridge (Saguache County, Colorado)
Built 1937
Wooden bridge over Dawson Creek on US 50
Unknown status

Delta Bridge (Delta County, Colorado)
Completed May 1924; parallel eastbound bridge built 1966; replaced 1992
Lost four-span through truss bridge over the Gunnison River on westbound US 50 at Delta
Replaced by modern bridge

Fifth Street Bridge (Mesa County, Colorado)
Built 1933 by the Wisconsin Steel & Iron Works; replaced 1989
Lost four-span through truss bridge over Colorado River on Northbound US 50 at Grand Junction
Replaced by new bridge

Goss Ditch US 50 Bridge (Jackson County, Indiana)
Built 1937
Concrete arch bridge over Goss Ditch on US 50
Open to traffic

Gunnison River Bridges (Gunnison County, Colorado)
Built 1927; replacement bridges built on new alignment in 1957
Pair of through trusses over the Gunnison River on Old US 50 just west of Gunnison
Open to traffic

Huerfano Bridge (Pueblo County, Colorado)
Built 1921; rehabilitated 1948
Five-span arch bridge over Huerfano River on US 50
Open to traffic

Lamine River Old US 50 Bridge (Cooper County, Missouri)
Built 1930
Open-spandrel arch bridge over Lamine River on Route A (Old US 50) east of Otterville
Open to traffic

Little Fork Little Sandy Creek Bridge (Preston County, West Virginia)
Built 1927
Concrete arch bridge over Little Fork Little Sandy Creek on US 50
Open to traffic

Little Muddy Creek Bridge (Clay County, Illinois)
Built 1923
Through truss bridge over Little Muddy Creek on Fr-2114 (Old US 50)
Closed to all Traffic

Little Wabash River Bridge (Clay County, Illinois)
Built 1923
Parker through truss bridge over Little Wabash River on Fr-2114 (Old US 50)
Closed to all Traffic

Little Wabash River Overflow Bridge (Clay County, Illinois)
Built 1923
Steel stringer bridge over Little Wabash River Overflow on Fr-2114 (Old US 50)
Closed to all traffic

Mount Sterling Bridge (Gasconade County, Missouri)
Lost through truss bridge over Gasconade River at Mount Sterling on US 50
Replaced 1979

Old Cleves Bridge (Hamilton County, Ohio)
Built 1914 by the Penn Bridge Co.; parallel bridge built 1959-60; closed to traffic Feb. 1988; replaced 1990
Lost four-span through truss bridge over the Great Miami River on eastbound US 50 at Cleves
Replaced by modern bridge

Old US 50 Viaduct (Cooper County, Missouri)
Built 1924
Tee beam bridge over the Union Pacific Railroad on Old US 50, just north of current US 50
Open to traffic

Osage River Bridge at Hubers Landing (Osage County, Missouri)
Lost vertical-lift through truss bridge over Osage River on US 63 and US 50
Replaced by new bridge

Rising Creek Bridge (Cole County, Missouri)
Built 1927
Concrete bridge over Rising Creek on Liberty Road (Old US 50/63)
Open to traffic

Rock Ford Canal Bridge (Pueblo County, Colorado)
Built 1932
Closed-spandrel arch bridge over Rocky Ford Hiland Canal on US 50
Open to traffic

Rouch Gulch Bridge (Fremont County, Colorado)
Built 1934 by the Gordon Construction Co.
Closed-spandrel arch bridge over Spring Creek on US 50
Open to traffic

Santa Fe Avenue Bridge (Pueblo County, Colorado)
Built 1924 by the Pueblo Bridge Co.
Through truss bridge over the Arkansas River on eastbound US 50 (Santa Fe Avenue) in Pueblo
Open to two lanes of traffic

Sinepuxent Bay Bridge (Worcester County, Maryland)
Built 1942
Bascule bridge over Sinepuxent Bay on US 50 in Ocean City
Open to traffic

South Branch Potomac River Bridge (Hampshire County, West Virginia)
Built 1936
Through truss bridge over South Branch Potomac River on US 50 T
Open to traffic

South Fork Leatherwood Creek US 50 Bridge (Lawrence County, Indiana)
Built 1932
Concrete arch bridge over South Fork Leatherwood Creek on US 50
Open to traffic

St. Charles River US 50 Bridge (Pueblo County, Colorado)
Built 1942; parallel eastbound bridge built 1971
Through truss bridge over St. Charles River on westbound US 50 in Pueblo
Open to two-lane westbound traffic

Stony River Bridge (Grant County, West Virginia)
Built 1931
Through truss bridge over Stony River on US 50
Open to traffic

US 50E Osage River Bridge (Cole County, Missouri)
Built 1998
Steel stringer bridge over Osage Rvr, Pvt Marina Road on Us 50 E Us 63 S
Open to traffic

US 50W Osage River Bridge (Osage County, Missouri)
Built 1958; rehabilitated 2002
Steel stringer bridge over Osage Rvr, Pvt Marina Road on Us 50 W and Us 63 N
Open to traffic

Vernon Fork US 50 Bridge (Jennings County, Indiana)
Built ca. 1930; rehabilitated 1996
Concrete arch bridge over Vernon Fork Muscatatuck River on US 50
Open to traffic

Vincennes Bridge (Lawrence County, Illinois)
Built 1931; rehabilitated 1992
Arch bridge over Wabash River on Business US 50 at Vincennes
Open to traffic

Watson-Lindbergh Cloverleaf Bridge (St. Louis County, Missouri)
Opened to traffic August 20, 1913; replaced 1983
Lost concrete arch bridge over Lindbergh Blvd. on Watson Road (formerly US 66) as part of the first cloverleaf interchange west of the Mississippi River
Replaced by new bridge

Wicomico River Bridge (Wicomico County, Maryland)
Built 1962
Bascule bridge over Wicomico River on Business US 50 in Salisbury
Open to traffic